Abstract not available for EP 1697381 (A1) Abstract of corresponding document: WO 2005061518 (A1)
The present invention relates to 2-phenylthienylpyrimidinone compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
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Mitotic kinesin inhibitors
Mitotic kinesin inhibitors
| Patent Number: EP1697381 (A1) | |
| Applicants: MERCK & CO INC [United States] details >>
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| Europe: A61K41/00; C07D495/04 | |
| Application number: EP20040814749 20041215 |
| Publication date: 2006-09-06 | |
| Inventors: ARRINGTON KENNETH L [United States]; FRALEY MARK E [United States]; HARTMAN GEORGE D [United States] details >>
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| International: A61K31/519; A61K41/00; A61P35/00; C07D495/04; A61K31/519; A61K41/00; A61P35/00; C07D495/00 | |
| Priority numbers: WO2004US42604 20041215; US20030531376P 20031219 |
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